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Use of hydroxychloroquine in hospitalized patients with coronavirus disease COVID especially in combination with azithromycin has raised safety concerns. Here we report safety data from outpatient randomized clinical trials.
Hydroxychloroquine total doses ranged between and mg treatment durations were from to days and follow up times between and days. Compared to controls hydroxychloroquine nonsignificantly increased mortality at days RR .
The most common adverse events of hydroxychloroquine and chloroquine are gastrointestinal upset along with nausea vomiting and diarrhea . In a study evaluating the use of chloroquine miglior prezzo per Tadacip of patients reported nauseaabdominal cramps and diarrhea as side effects .
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webMain conclusions. The current evidence on the efficacy and safety of hydroxychloroquine for the treatment of COVID is limited and of very low certainty. Hydroxychloroquine was not associated with a difference in overall mortality when compared to standard care for the treatment of COVID.
Lanalisi mostra che lHCQ con o senza azitromicina non riduce il rischio di evoluzione verso la ventilazione meccanica e al contrario si osserva un aumento del rischio di mortalit complessiva HR CI P nei pazienti trattati con HCQ da sola rispetto ai pazienti non trattati con HCQ.
Some researchers have promoted chloroquine and hydroxychloroquine for the treatment and prevention of illness from a variety of microorganisms including SARSCoV. Hydroxychloroquine can
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